In this simulation activity, students decide which of two companies, each using a different CRISPR genome-editing technology, to invest in. They engage with research on CRISPR genome editing to understand how unintended consequences of one technology used for this editing had real-world business implications. The storytelling element adds immediacy to the activity, making it imaginative and engaging, and students are pushed toward achieving higher levels of competence within Bloom’s taxonomy for the subject area.
This case study, contributed by the Cornell Center for Teaching Excellence, is intended to show that two enantiomers can have different effects on the body, and how the same drug can be used to treat different diseases or symptoms. It is also intended to help students begin to understand the process of FDA approval for drugs. This problem could be used in an organic chemistry class or in a class for non-science majors.